Makoto Suematsu Selected Research

hypotaurine

1/2022	The hypotaurine-taurine pathway as an antioxidative mechanism in patients with acute liver failure.
1/2018	Gold-nanofève surface-enhanced Raman spectroscopy visualizes hypotaurine as a robust anti-oxidant consumed in cancer survival.
3/2010	Hypotaurine is an Energy-Saving Hepatoprotective Compound against Ischemia-Reperfusion Injury of the Rat Liver.

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Makoto Suematsu Research Topics

Disease

45	Neoplasms (Cancer) 01/2022 - 01/2006
23	Hypoxia (Hypoxemia) 12/2021 - 11/2005
13	Inflammation (Inflammations) 06/2021 - 01/2004
11	Ischemia 11/2019 - 08/2002
7	Adenoma (Adenomas) 01/2022 - 05/2010
7	Colonic Neoplasms (Colon Cancer) 01/2022 - 01/2010
6	Neoplasm Metastasis (Metastasis) 01/2022 - 05/2010
6	Reperfusion Injury 04/2015 - 01/2010
5	Hyperaldosteronism (Conn Syndrome) 12/2021 - 01/2016
5	Interstitial Nephritis (Tubulointerstitial Nephritis) 01/2016 - 05/2003
4	Colorectal Neoplasms (Colorectal Cancer) 01/2022 - 05/2010
4	Carcinoma (Carcinomatosis) 01/2021 - 01/2006
4	Heart Failure 01/2018 - 02/2005
4	Fatty Liver 02/2012 - 03/2004
3	Lung Neoplasms (Lung Cancer) 01/2022 - 10/2011
3	Insulin Resistance 01/2021 - 03/2004
3	Colitis 01/2021 - 02/2008
3	Carcinogenesis 01/2021 - 10/2014
3	Glioma (Gliomas) 01/2020 - 10/2014
3	Hypertrophy 01/2019 - 07/2007
3	Cardiomegaly (Heart Hypertrophy) 01/2018 - 07/2007
3	Hyperhomocysteinemia 08/2015 - 07/2008
3	Cardiovascular Diseases (Cardiovascular Disease) 08/2015 - 11/2009
3	Non-alcoholic Fatty Liver Disease 02/2015 - 01/2010
3	Homocystinuria 06/2014 - 08/2010
2	Acute Liver Failure (Fulminant Hepatic Failure) 01/2022 - 11/2021
2	Disease Progression 01/2022 - 01/2019
2	Vascular Remodeling 01/2022 - 01/2002
2	Infections 11/2021 - 01/2019
2	Ovarian Neoplasms (Ovarian Cancer) 08/2021 - 01/2021
2	Pain (Aches) 01/2020 - 10/2019

Drug/Important Bio-Agent (IBA)

19	Proteins (Proteins, Gene)FDA Link 01/2022 - 05/2003
16	Glucose (Dextrose)FDA LinkGeneric 01/2022 - 04/2007
13	EnzymesIBA 01/2022 - 01/2002
13	Oxygen (Dioxygen)IBA 01/2022 - 09/2006
10	Glutathione (Reduced Glutathione)IBA 01/2022 - 11/2009
9	Reactive Oxygen Species (Oxygen Radicals)IBA 11/2019 - 01/2006
8	LipidsIBA 01/2022 - 01/2010
8	Fatty Acids (Saturated Fatty Acids)IBA 01/2022 - 02/2015
8	AldosteroneIBA 01/2022 - 05/2010
8	CystathionineIBA 01/2021 - 01/2011
8	CytokinesIBA 01/2019 - 11/2005
7	AntigensIBA 01/2022 - 05/2003
7	Heme (Haem)IBA 06/2021 - 08/2002
7	Amino Acids FDA Link 01/2021 - 03/2010
6	Cytochrome P-450 CYP11B2 (CYP11B2)IBA 01/2022 - 05/2010
6	Biomarkers (Surrogate Marker)IBA 01/2022 - 03/2010
6	ErbB Receptors (EGF Receptor)IBA 07/2021 - 01/2016
6	Adenosine Triphosphate (ATP)IBA 11/2019 - 01/2010
5	Biological ProductsIBA 01/2022 - 05/2010
5	Carbon MonoxideIBA 06/2021 - 01/2002
5	Progesterone Receptors (Progesterone Receptor)IBA 06/2021 - 03/2016
5	Nitric Oxide (Nitrogen Monoxide)FDA Link 05/2016 - 01/2002
5	Messenger RNA (mRNA)IBA 10/2014 - 08/2002
4	Immune Checkpoint InhibitorsIBA 01/2022 - 01/2019
4	Pharmaceutical PreparationsIBA 01/2022 - 09/2015
4	Mixed Function Oxygenases (Monooxygenases)IBA 01/2022 - 01/2002
4	Glutamic Acid (Glutamate)FDA Link 07/2018 - 04/2014
4	AntioxidantsIBA 01/2018 - 03/2012
4	Methionine (L-Methionine)FDA Link 06/2016 - 01/2011
4	LipocalinsIBA 01/2016 - 11/2009
4	Cysteine (L-Cysteine)FDA Link 04/2015 - 07/2008
3	Therapeutic UsesIBA 01/2022 - 02/2007
3	Taurine FDA Link 01/2022 - 03/2010
3	hypotaurineIBA 01/2022 - 03/2010
3	Phospholipids (Phosphatides)FDA LinkGeneric 01/2022 - 06/2011
3	Phosphotransferases (Kinase)IBA 07/2021 - 01/2015
3	GlucocorticoidsIBA 01/2021 - 01/2002
3	LyasesIBA 01/2021 - 05/2012
3	Dopamine (Intropin)FDA LinkGeneric 01/2020 - 01/2018
3	NAD (NADH)IBA 11/2019 - 01/2002
3	Indicators and Reagents (Reagents)IBA 01/2019 - 03/2004
3	CarbonIBA 12/2018 - 05/2015
3	Protein Isoforms (Isoforms)IBA 12/2018 - 06/2012
3	AldehydesIBA 10/2018 - 11/2009
3	Lactic Acid (Lactate)FDA LinkGeneric 08/2017 - 04/2007
3	Steroid 11-beta-Hydroxylase (11 beta-Hydroxylase)IBA 03/2017 - 05/2010
3	NADP (NADPH)IBA 04/2016 - 01/2002
3	Cystine (L-Cystine)IBA 01/2016 - 06/2012
2	NucleotidesIBA 01/2022 - 05/2010
2	Phospholipases A2 (Phospholipase A2)IBA 01/2022 - 01/2021
2	CholesterolIBA 01/2022 - 11/2020
2	Nonesterified Fatty Acids (NEFA)IBA 01/2022 - 01/2013
2	Leucine (L-Leucine)FDA Link 01/2022 - 04/2014
2	CateninsIBA 01/2022 - 12/2021
2	Acetaminophen (Paracetamol)FDA LinkGeneric 11/2021 - 08/2012
2	polysulfideIBA 08/2021 - 01/2021
2	purineIBA 07/2021 - 05/2010
2	Cisplatin (Platino)FDA LinkGeneric 06/2021 - 01/2021
2	SulfurIBA 01/2021 - 10/2018
2	PlatinumIBA 01/2021 - 11/2016
2	LigandsIBA 11/2020 - 03/2004
2	Polysaccharides (Glycans)IBA 08/2020 - 01/2016

Therapy/Procedure

10	Therapeutics 01/2022 - 07/2011
5	Transplantation 09/2020 - 02/2005
5	Lasers (Laser) 12/2018 - 02/2002
4	Immunotherapy 01/2022 - 01/2020
3	Heterologous Transplantation (Xenotransplantation) 06/2021 - 06/2011
3	Oral Administration 09/2015 - 01/2010
2	Drug Therapy (Chemotherapy) 01/2021 - 07/2005